Nolan Arenado hit a two-run homer over the Green Monster in the first inning and the St. Louis Cardinals broke it open with a six-run sixth in an 11-2 victory over the Boston Red Sox on Saturday night.

Nolan Gorman and Tyler O’Neill both had a solo shot for the Cardinals, who rebounded after losing the opener of the three-game series. Paul Goldschmidt and Tommy Edman each had a two-run single during the big inning.

It snapped the Cardinals’ five-game losing streak in Fenway Park – including the final game when Boston won the ’13 Series – and was their first win here since Game 2 on Oct. 24, 2013.

Dakota Hudson (5-3) held Boston to two runs in five innings.

Arenado homered into the first row of seats against Kutter Crawford (1-2). Gorman and O’Neill each hit theirs into the center-field bleachers.

Coming off five shutout innings for his first big-league victory in his previous start, Crawford gave up four runs in four innings.

UP NEXT

RHP Andre Pallante (2-1, 1.46 ERA) is set to come out of the bullpen and start for the Cardinals in Sunday’s series finale. RHP Nick Pivetta (6-5, 3.50) looks to continue his recent hot stretch for the Red Sox. He’s 6-1 with a 1.83 ERA in his last eight starts. The finale of the three-game series is set to begin at 12:35 in Fenway Park.